How long does it take for neutrophils to infiltrate a clot during first intention healing according to Weiseberger's method?

In first intention healing, which is the primary method of wound healing for clean surgical incisions, neutrophils are one of the first responders to an injury. According to Weiseberger's method, neutrophils typically infiltrate the area within a timeframe of 3 to 24 hours after the injury occurs.

During this period, they play a critical role in preventing infection by phagocytosing bacteria and debris, which sets the stage for the subsequent phases of healing. This initial infiltration occurs quite rapidly to address the immediate threat of infection and is crucial in the inflammatory response.

The options that indicate a shorter time frame do not fully align with the typical physiological response, as neutrophil migration often requires a few hours to become evident at the injury site. Similarly, the options that extend beyond 24 hours may be more indicative of later stages of healing or other cell types, such as macrophages and lymphocytes, which follow after neutrophils in the healing process. Hence, the correct answer captures the accurate timeframe for neutrophil infiltration during first intention healing according to the established method.