What type of necrosis is characterized by a "cheesy" appearance?

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Caseous necrosis is characterized by a "cheesy" appearance due to the accumulation of necrotic tissue that has a dry, crumbly texture reminiscent of cheese. This type of necrosis is typically associated with tuberculosis infections, where the necrotic tissue contains dead macrophages and other immune cells that have surrounded the mycobacteria. The term "caseous" itself is derived from the Latin word for cheese, emphasizing the distinctive texture.

The processes involved in caseous necrosis include the formation of granulomas as the body attempts to wall off the infectious agents. This results in a central area of necrotic tissue that is often surrounded by a rim of activated macrophages, lymphocytes, and fibroblasts. As the cell debris accumulates and the lipid content increases, it contributes to the characteristic appearance.

In comparison, liquefactive necrosis involves the transformation of tissue into a liquid viscous mass, typically seen in brain injuries or bacterial infections. Coagulative necrosis features a solid, firm texture and is most commonly seen in ischemic events, like myocardial infarction. Fat necrosis occurs due to the breakdown of lipids and is often associated with pancreatic damage or trauma, presenting a different histological pattern.

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