What type of necrosis is primarily seen in myocardial infarction?

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Coagulative necrosis is the type of necrosis primarily associated with myocardial infarction. This form of necrosis occurs due to an interruption of blood supply, leading to tissue ischemia. In the case of myocardial infarction, there is an acute loss of blood flow to the cardiac muscle, which results in the death of myocardial cells.

During coagulative necrosis, the architecture of the tissue remains somewhat preserved initially, despite the death of the cells. The cell outlines can still be recognized, but the cellular details are lost due to protein denaturation and the coagulation of cellular components. This is in stark contrast to liquefactive necrosis, where the tissue becomes liquid and the architecture is lost, and to caseous necrosis, which has a cheese-like appearance typically seen in tuberculosis infections. Fat necrosis is associated with the breakdown of fat tissues, often due to trauma or pancreatitis, which is unrelated to myocardial infarction.

In summary, the specific pathophysiological changes that occur during myocardial infarction lead to coagulative necrosis, making it the correct choice in this context.

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